ICD-10 Codes for Neoplasms (C00-D49): A Comprehensive Overview
ICD-10 Codes for Neoplasms (C00-D49): A Comprehensive Overview
11 Jan 2022
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8 min
Neoplasms, commonly known as tumors, are abnormal growths of cells that can either be benign (non-cancerous) or malignant (cancerous). The ICD-10 code C00-D49 is dedicated to classifying and documenting neoplasm growths within the human body.
This extensive range includes codes for various types of neoplasms, their locations, behavior (benign, malignant, or uncertain), and specific characteristics. Read on to learn about the key diagnosis under each classification.
ICD-10-CM Code C00-C97: Malignant Neoplasms
A malignant neoplasm, commonly known as cancer, is a type of abnormal growth or tumor characterized by uncontrolled cell division and the potential to invade surrounding tissues or spread to other parts of the body.
One distinguishing feature of malignant neoplasms is their ability to invade nearby tissues. They can penetrate surrounding structures, causing damage and compromising organ function.
Furthermore, malignant cells can break away from the primary tumor and travel through the bloodstream or lymphatic system to form secondary tumors in distant organs or tissues—a process known as metastasis.
Key ICD-10-CM Codes for Malignant Neoplasms
ICD Code
Description
Diagnosis
ICD Code C00
Malignant neoplasm of lip
This code represents malignant tumors that originate in the lip. These cancers are often associated with prolonged sun exposure and may occur more frequently in fair-skinned individuals.
ICD Code C16
Malignant neoplasm of stomach
Stomach cancer is a malignant tumor that develops in the stomach lining. It can result from various factors, including Helicobacter pylori infection, diet, and genetics.
ICD Code C18
Malignant neoplasm of colon
Colon cancer is a common malignancy that affects the colon or large intestine. Risk factors include age, family history, and dietary factors.
ICD Code C34
Malignant neoplasm of bronchus and lung
Lung cancer is often associated with tobacco smoking and carcinogen exposure. It includes various types, such as non-small cell lung cancer and small cell lung cancer
ICD Code C50
Malignant neoplasm of breast
Breast cancer is a prevalent cancer type in women, characterized by the abnormal growth of breast tissue cells. It can occur in both men and women but is more common in the latter.
ICD Code C53
Malignant neoplasm of cervix uteri
Cervical cancer develops in the cervix, often associated with persistent human papillomavirus (HPV) infection. Regular screenings can help with early detection.
ICD Code C56
Malignant neoplasm of ovary
Ovarian cancer involves malignant tumors originating in the ovaries. It can be challenging to detect in its early stages.
ICD Code C61
Malignant neoplasm of the prostate
Prostate cancer affects the prostate gland in men and is one of the most common cancers among men. Risk factors include age and family history.
ICD Code C67
Malignant neoplasm of bladder
Bladder cancer arises in the cells of the bladder lining. Risk factors include smoking and exposure to certain chemicals.
An in situ neoplasm, also known as carcinoma in situ (CIS), refers to a stage of cancer development in which abnormal cells are found only in the location where they first formed and have not invaded nearby tissues.
In situ neoplasms are often considered a precancerous or very early cancer stage. While the cells are abnormal, they have not crossed the basement membrane or barrier that separates them from nearby tissues.
Key ICD-10-CM Codes for In Situ Neoplasms
ICD Code
Description
Diagnosis
ICD Code D00
Carcinoma in Situ of Oral Cavity
Carcinoma in situ of the oral cavity refers to the abnormal cells in the mouth that have not yet invaded surrounding tissues.
ICD Code D01
Carcinoma in Situ of Other Digestive Organs
Carcinoma in situ of other digestive organs indicates the presence of abnormal cells in the digestive system without invasion into adjacent tissues..
ICD Code D02
Carcinoma in Situ of Middle Ear and Respiratory System
Carcinoma in situ of the middle ear and respiratory system involves abnormal cell growth in these areas without infiltration into neighboring structures.
ICD Code D03
Melanoma in Situ
Melanoma in situ refers to the early stage of melanoma skin cancer where malignant melanocytes are present only in the epidermis.
ICD Code D04
Carcinoma in Situ of Skin
Carcinoma in situ of the skin indicates the presence of abnormal skin cells that have not yet penetrated deeper layers.
ICD Code D05
Carcinoma in Situ of Breast
Carcinoma in situ of the breast involves abnormal cell growth in breast ducts or lobules without invasive characteristics..
ICD Code D06
Carcinoma in Situ of Cervix Uteri
Carcinoma in situ of the cervix uteri is an early stage of cervical cancer where abnormal cells are confined to the cervical lining.
ICD Code D07
Carcinoma in Situ of Other Female Genital Organs
Carcinoma in situ of other female genital organs implies the presence of abnormal cells in these organs without invasion into surrounding tissues.
ICD Code D08
Carcinoma in Situ of Urinary Organs
Carcinoma in situ of urinary organs involves abnormal cell growth in the urinary system without spreading to nearby structures.
ICD Code D09
Carcinoma in Situ of Other Sites
Carcinoma in situ of other sites encompasses abnormal cell growth in various locations that have not yet invaded neighboring areas.
ICD-10-CM Code D10-D36: Benign Neoplasms
Benign neoplasms are non-cancerous growths or tumors that arise from abnormal cell proliferation but do not have the capacity to invade nearby tissues or metastasize to distant parts of the body. They are generally considered less aggressive and less harmful than malignant neoplasms.
Benign neoplasms can occur in extensive tissues and organs, including the skin, soft tissues, glands, and more. Each type of benign neoplasm is assigned a specific code within the D10-D36 range based on its location and characteristics.
Key ICD-10-CM Codes for Benign Neoplasms
ICD Code
Description
Diagnosis
ICD Code D10
Benign Neoplasm of Mouth and Pharynx
Benign neoplasm of the mouth and pharynx refers to non-cancerous growths in the oral and throat areas.
ICD Code D11
Benign Neoplasm of Major Salivary Glands
Benign neoplasm of major salivary glands indicates non-malignant growths in the larger salivary glands, such as the parotid gland.
ICD Code D12
Benign Neoplasm of Colon, Rectum, Anus, and Anal Canal
Benign neoplasm of the colon, rectum, anus, and anal canal involves non-cancerous growths in the lower digestive tract.
ICD Code D13
Benign Neoplasm of Other Parts of Digestive Tract
Benign neoplasm of other parts of the digestive tract encompasses non-malignant growths in various areas of the gastrointestinal system.
ICD Code D14
Benign Neoplasm of Middle Ear and Respiratory System
Benign neoplasm of the middle ear and respiratory system indicates non-cancerous growth in these regions.
ICD Code D15
Benign Neoplasm of Other Intrathoracic Organs
Benign neoplasm of other intrathoracic organs involves non-malignant growths in the chest area apart from the lungs..
ICD Code D16
Benign Neoplasm of Bone and Articular Cartilage
Benign neoplasm of bone and articular cartilage refers to non-cancerous growths affecting bones and joint cartilage.
ICD Code D17
Benign Lipomatous Neoplasms
Benign lipomatous neoplasms are non-malignant fatty tissue growths.
ICD Code D18
Hemangioma and Lymphangioma, Any Site
Hemangiomas and lymphangiomas are benign neoplasms involving blood vessels or lymphatic vessels and can occur in various body locations.
ICD Code D36
Benign Neoplasm of Other and Unspecified Sites
Benign neoplasm of other and unspecified sites encompasses non-cancerous growths in locations not covered by the previous categories.
Uncertain Behavior Neoplasms are a category of abnormal tissue growths that exhibit characteristics of a neoplasm (tumor) but with uncertainty regarding whether they are benign (non-cancerous) or malignant (cancerous). These neoplasms have a well-defined histological appearance, meaning their cellular structure and features are identifiable, but their subsequent behavior is difficult to predict.
Key ICD-10-CM Codes for Uncertain Behavior Neoplasms
ICD Code
Description
ICD Code D37.0
Neoplasm of uncertain behavior of the oral cavity and digestive organs
ICD Code D37.1
Neoplasm of uncertain behavior of the respiratory and intrathoracic organs
ICD Code D37.2
Neoplasm of uncertain behavior of the bone and articular cartilage
ICD Code D37.3
Neoplasm of uncertain behavior of connective and soft tissue
ICD Code D37.4
Neoplasm of uncertain behavior of skin
ICD Code D37.5
Neoplasm of uncertain behavior of breast
ICD Code D37.6
Neoplasm of uncertain behavior of other specified sites
ICD Code D37.7
Neoplasm of uncertain behavior of endocrine glands and related structures
ICD Code D37.8
Neoplasm of uncertain behavior of overlapping sites
ICD Code D37.9
Neoplasm of uncertain behavior of unspecified site
Accurate coding of neoplasms within the C00-D49 range is crucial in oncology. It ensures proper patient care, contributes to research, and facilitates fair reimbursement for healthcare providers. By knowing what ICD-10 codes C00-D49 for neoplasms cover, healthcare professionals can advance cancer care through precise documentation.
Disclaimer: The information provided in this blog regarding the International Classification of Diseases (ICD) codes is intended for informational purposes only.We strive to offer accurate and up-to-date content. However, the ICD codes are subject to changes, updates, and modifications by authoritative bodies such as the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and other relevant healthcare organizations. These changes can occur due to advancements in medical knowledge, new diseases, evolving diagnostic criteria, or updates in medical terminology.
FAQs
What is the purpose of ICD-10 codes for neoplasms in healthcare?
ICD-10 codes for neoplasms serve the purpose of categorizing and coding these conditions accurately, facilitating proper patient care, research, and statistical analysis.
How do ICD-10 codes assist in cancer research and statistics?
ICD-10 codes enable researchers to analyze trends, outcomes, and the effectiveness of cancer treatments, contributing to advancements in cancer research and statistics.
What are the coding challenges associated with rare or unusual neoplasms?
Coding rare or unusual neoplasms can be challenging due to limited documentation and less common diagnostic criteria. Healthcare providers must rely on their expertise and available information.
Are there updates or changes in ICD-10 codes for neoplasms in recent years?
ICD-10 codes are periodically updated to reflect advancements in medical knowledge and changes in disease classification. Healthcare professionals should stay informed about these updates to ensure accurate coding.
