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ICD 10 Code for Endocrine and Metabolic Diseases: Range (E00-E89

ICD 10 Code for Endocrine and Metabolic Diseases: Range (E00-E89

11 Jan 2022
7 min
ICD 10 Code for Endocrine and Metabolic Diseases: Range (E00-E89)

ICD-10 Code E00-E89 encompasses an array of endocrine, nutritional, and metabolic diseases classified by the World Health Organization (WHO). These codes are vital for healthcare professionals and medical coders in accurately documenting and billing for the endocrine system, nutrition, and metabolism-related conditions. 

But what exactly is the endocrine and metabolic system?

  • Endocrine: Think of the endocrine system as your body's messaging organs. It uses hormones (like tiny messengers) to tell different parts of your body what to do. These hormones control things like your growth, mood, and how you use energy. When something goes wrong with these messengers or how the body responds to them, it can lead to endocrine diseases like diabetes or thyroid problems.
  • Metabolic System: Your metabolic system is like your body's energy manager. It takes charge of what you eat by turning it into the energy your body needs to function. It's also responsible for deciding how to store or use that energy. If your metabolic system fails, it can lead to metabolic diseases like obesity and high cholesterol.

Further Reading:

ICD-10-CM Code E00-E07 - Disorders of Thyroid Gland

The thyroid, a butterfly-shaped endocrine gland located in the front of the neck, is a vital endocrine organ responsible for regulating metabolism and various bodily functions by producing and releasing thyroid hormones. Disorders of the thyroid gland affect its structure or function.

Key ICD-10-CM Codes for Disorders of Thyroid Gland
ICD Code Description Diagnosis
ICD Code E03.9 Hypothyroidism, Unspecified Unspecified hypothyroidism, indicating a low production of thyroid hormones
ICD Code E01 Iodine-deficiency-related thyroid disorders and allied conditions This code is used for thyroid disorders resulting from iodine deficiency and related conditions
ICD Code E02 Subclinical iodine-deficiency hypothyroidism Subclinical hypothyroidism resulting from iodine deficiency
ICD Code E03 Other hypothyroidism Various forms of hypothyroidism that are not related to iodine deficiency, such as Hashimoto's thyroiditis
ICD Code E04 Other non-toxic goiters Non-toxic goiter, which is the enlargement of the thyroid gland, not caused by excessive thyroid hormone production or iodine deficiency
ICD Code E05 Thyrotoxicosis (hyperthyroidism) Hyperthyroidism or when the thyroid gland produces an excess of thyroid hormones
ICD Code E06 Thyroiditis Inflammation of the thyroid gland and various types of thyroiditis
ICD Code E07 Other disorders of the thyroid This code encompasses other thyroid disorders that don't fall into the previous categories, such as benign neoplasms or cysts of the thyroid

ICD-10-CM Code  E08-E13: Diabetes Mellitus

Diabetes Mellitus is a chronic medical condition characterized by elevated blood sugar levels resulting from the body's inability to effectively produce or utilize insulin, a hormone responsible for regulating blood glucose.

Key ICD-10-CM Codes for Diabetes Mellitus
ICD Code Description Diagnosis
E08.9 Diabetes Mellitus Due to Underlying Condition without Complications Diabetes mellitus resulting from an underlying condition without associated complications
E10.9 Type 1 Diabetes Mellitus without Complications Type 1 diabetes without any specified complications
E11.9 Type 2 Diabetes Mellitus without Complications Type 2 diabetes without any specified complications
E12.9 Malnutrition-Related Diabetes Mellitus without Complications Diabetes mellitus related to malnutrition without specified complications
E13.9 Other Specified Diabetes Mellitus without Complications Other specified forms of diabetes mellitus without any associated complications
E09.9 Drug or Chemical-Induced Diabetes Mellitus without Complications Diabetes mellitus induced by drugs or chemicals without specified complications
E08.21 Diabetes Mellitus Due to Underlying Condition with Diabetic Nephropathy Diabetes mellitus resulting from an underlying condition with the complication of diabetic nephropathy (kidney disease)
E10.65 Type 1 Diabetes Mellitus with Hyperglycemia Type 1 diabetes with hyperglycemia (elevated blood sugar) as a specific complication
E11.65 Type 2 Diabetes Mellitus with Hyperglycemia Type 2 diabetes with hyperglycemia as a specific complication
E12.65 Malnutrition-Related Diabetes Mellitus with Hyperglycemia Diabetes mellitus related to malnutrition with hyperglycemia as a specific complication

ICD-10-CM Code E15-E16: Other Disorders of Glucose Regulation

Conditions within this category may include various forms of hyperglycemia (high blood sugar) or hypoglycemia (low blood sugar) not attributed to the typical mechanisms seen in diabetes. They can also encompass pancreatic disorders affecting insulin production or other hormones involved in glucose regulation.

Key ICD-10-CM Codes for Other Disorders
ICD Code Description Diagnosis
E15.0 Non Diabetic Hypoglycemia, without Coma Hypoglycemia (low blood sugar) not related to diabetes, without the presence of a coma
E16.2 Hypoglycemia, Unspecified Unspecified hypoglycemia, which indicates low blood sugar levels without specifying a known cause
E15.2 Other Specified Hypoglycemia Hypoglycemia with a specific cause or origin that is stated
E16.1 Other Hypoglycemia Hypoglycemia due to various causes not specifically mentioned in other categories
E15.8 Other Specified Disorders of Glucose Regulation and Pancreatic Internal Secretion Other specified disorders affecting the regulation of blood glucose levels and pancreatic hormone secretion
E16.3 Increased Insulin Requirements Conditions where the body requires higher insulin levels, potentially due to factors such as insulin resistance
E15.5 Other Post-Surgical Panhypopituitarism A condition characterized by the underproduction of hormones by the pituitary gland after surgery, affecting glucose regulation
E16.0 Drug-Induced Hypoglycemia without Coma Hypoglycemia resulting from the use of specific drugs or medications, without the presence of a coma
E15.9 Other and Unspecified Disorders of Glucose Regulation and Pancreatic Internal Secretion Condition affecting glucose regulation and pancreatic hormone secretion that are not further specified
E16.4 Hypoglycemia, Unspecified with Coma Severe hypoglycemia with the presence of a coma, the cause of which is not specifically mentioned

ICD-10-CM Code E20-E35: Disorders of Other Endocrine Glands

Disorders within this category may involve overproduction, underproduction, or dysfunction of these hormones and can affect different endocrine glands such as the adrenal glands, parathyroid glands, pituitary glands, and others.

Key ICD-10-CM Codes for Disorders of Other Endocrine Glands
ICD Code Description Diagnosis
E28.0 Androgen Insensitivity Syndrome A genetic disorder in which an individual with male chromosomes (XY) is unresponsive to male sex hormones (androgens).
E29.1 Testicular Hypofunction Reduced function of the testes, resulting in insufficient production of testosterone
E30.1 Autoimmune Polyglandular Syndrome A rare autoimmune disorder that affects multiple endocrine glands, often leading to hormone deficiencies.
E31.0 Autoimmune Proliferative Syndrome A condition characterized by the overgrowth of endocrine tissues due to autoimmune mechanisms
E34.3 Short Stature due to Endocrine Disorder Growth impairment caused by an underlying endocrine disorder
E32.0 Non-Functioning Pituitary Tumor A pituitary tumor that does not secrete hormones, often leading to pressure on nearby structures.
E26.9 Hyperaldosteronism, Unspecified A condition marked by excessive secretion of aldosterone, often resulting in high blood pressure.
E25.9 Adrenogenital Disorders, Unspecified Unspecified disorders related to the adrenal glands and their impact on sexual development and function

ICD-10-CM Code E36-E46: Nutrition-Related Metabolic Disorders

This category is used for the classification and documentation of various medical conditions that are primarily caused by abnormalities in the body's metabolism and nutrient processing. These disorders often result from genetic or acquired factors that affect the body's ability to metabolize essential nutrients, such as proteins, carbohydrates, and fats, leading to imbalances in various metabolic pathways.

Key ICD-10-CM Codes for Nutrition-Related Metabolic Disorders
ICD Code Description Diagnosis
E36.0 Phenylketonuria An inherited disorder that impairs the body's ability to metabolize the amino acid phenylalanine
E71.101 Maple Syrup Urine Disease, Classic Type A rare genetic disorder in which the body cannot process certain amino acids properly, resulting in a distinctive sweet odor in the urine
E74.09 Other Disorders of Carbohydrate Transport and Metabolism Various disorders affecting the processing and utilization of carbohydrates in the body
E78.0 Pure Hypercholesterolemia An inherited condition characterized by abnormally high levels of cholesterol in the blood
E88.01 Lipoprotein Lipase Deficiency A genetic disorder that affects the metabolism of lipids, leading to high triglyceride levels in the blood
E74.39 Other Disorders of Fatty-Acid Metabolism Various conditions related to the metabolism of fatty acids in the body
E72.11 Disorders of Ornithine Metabolism Conditions that disrupt the metabolism of the amino acid ornithine, potentially leading to hyperammonemia
E40 Kwashiorkor A severe form of malnutrition characterized by a lack of protein intake, resulting in edema and other symptoms
E63.9 Nutritional Deficiency, Unspecified A general code for nutritional deficiencies without specifying the particular nutrient deficiency
E46 Unspecified Protein-Calorie Malnutrition A code used for cases of malnutrition-related to inadequate protein and calorie intake without further specification

ICD-10-CM Code E50-E64: Other Nutritional Deficiencies

This range is used to classify and document a variety of medical conditions that result from inadequate intake, absorption, or utilization of essential nutrients, such as vitamins and minerals, in an individual's diet. These deficiencies can lead to a range of health problems and symptoms, depending on the specific nutrient involved.

Key ICD-10-CM Codes for Other Nutritional Deficiencies
ICD Code Description Diagnosis
E50.9 Vitamin A Deficiency, Unspecified A condition resulting from insufficient intake of vitamin A, leading to various symptoms and potential health issues
E51.2 Vitamin C Deficiency A deficiency in vitamin C (ascorbic acid) which can result in scurvy and a range of symptoms
E52 Niacin Deficiency A deficiency of niacin (vitamin B3), leads to pellagra, a condition characterized by dermatitis, diarrhea, and dementia
E53.8 Deficiency of Other Specified B Group Vitamins Insufficiency of specific B vitamins, not otherwise specified
E55 Vitamin D Deficiency A deficiency in vitamin D, which plays a crucial role in calcium metabolism and bone health
E58 Dietary Calcium Deficiency A deficiency of dietary calcium can lead to osteoporosis and other calcium-related health issues
E60.1 Iron Deficiency Anemia, Secondary to Blood Loss (Chronic) Anemia resulting from chronic blood loss, leading to insufficient iron levels in the body
E63.1 Iron Deficiency Anemia, Other Anemia is caused by iron deficiency, not due to chronic blood loss.
E65 Localized Adiposity Excessive localized body fat in certain areas, typically due to imbalances in fat metabolism
E64.9 Sequelae of Malnutrition Health conditions and complications that arise as a result of prior malnutrition

ICD-10-CM Code E65-E68: Overweight, Obesity, and Other Hyperalimentation

Overweight and obesity are significant public health concerns, as they are linked to various health complications such as heart disease, diabetes, and more. This range is used to classify and document a range of medical conditions associated with excess body weight, particularly overweight and obesity. It also covers conditions resulting from excessive food consumption and related factors, which can contribute to weight gain.

Key ICD-10-CM Codes for Overweight, Obesity, and Other Hyperalimentation
ICD Code Description Diagnosis
E66.9 Obesity, Unspecified Generalized code for unspecified obesity, indicating excessive body weight without specifying the degree or cause
E66.01 Morbid (Severe) Obesity due to Excess Calories Severe obesity primarily resulting from excessive caloric intake
E66.9 Overweight Overweight without specifying the degree or cause. Overweight refers to a body mass index (BMI) above the normal range but not in the obese category.
E66.3 Overweight due to Insulin Resistance Overweight condition primarily associated with insulin resistance
E67.3 Hypoventilation, Obesity-Hypoventilation Syndrome A condition often associated with severe obesity, where individuals may experience inadequate ventilation due to excess weight.
E68.0 Hyperalimentation Conditions resulting from the excessive intake of nutrients, which can lead to excessive body weight
E65.9 Localized Adiposity Accumulation of excess fat in localized areas is often referred to as "body fat bulges"
E65.0 Localized Adiposity Due to Excess Calories Accumulation of localized body fat primarily resulting from excessive calorie intake
E67.8 Other Hyperalimentation Conditions associated with excessive nutrient intake not specified in other categories
E68.2 Other Hyperalimentation Conditions resulting from excessive consumption of nutrients, not otherwise specified in specific categories

ICD-10-CM Code E70-E88: Metabolic Disorders

Metabolic disorders within ICD-10-CM E70-E88 include a wide spectrum of conditions, such as inborn errors of metabolism (genetic disorders that impair metabolic pathways), disorders affecting specific enzymes, and conditions related to the processing of various substances like carbohydrates, proteins, and lipids. 

This range is used to classify and document a diverse group of medical conditions that primarily result from abnormalities in the body's metabolic processes.

Key ICD-10-CM Codes for Metabolic Disorders
ICD Code Description Diagnosis
E74.00 Glycogen Storage Disease, Unspecified A group of genetic disorders that affect the storage and use of glycogen, resulting in various symptoms and complications
E70.9 Disorder of Amino-Acid Transport, Unspecified A condition related to the transport of amino acids, which may lead to metabolic imbalances
E74.10 Cystinosis, Unspecified A rare genetic disorder that causes an abnormal buildup of the amino acid cystine in the cells and tissues
E78.0 Pure Hypercholesterolemia An inherited condition characterized by abnormally high levels of cholesterol in the blood
E88.09 Other Disorders of Plasma-Protein Metabolism, Not Elsewhere Classified Conditions affecting the metabolism of plasma proteins, not further specified
E72.0 Disorders of Amino-Acid Transport Conditions that affect the transport of amino acids in the body, potentially leading to metabolic disturbances
E75.52 Other Sphingolipidosis A group of genetic disorders characterized by the buildup of sphingolipids in cells and tissues
E83.0 Disorders of Mineral Metabolism Conditions affecting the metabolism and regulation of minerals in the body, such as calcium and phosphorus
E74.81 Other Mucopolysaccharidoses A group of genetic disorders characterized by the abnormal storage of mucopolysaccharides, leading to various health problems
E75.21 Fabry's Disease A rare genetic disorder that results in the buildup of a specific fatty substance (glycosphingolipid) in various organs and tissues

Further Reading: 

Conclusion

ICD-10 Code range E00-E89 is a critical classification system for healthcare professionals and medical coders, as it provides a comprehensive framework for documenting and diagnosing endocrine and metabolic diseases. These diseases encompass a wide spectrum of conditions that affect the body's hormonal and metabolic processes, with implications for various organs and systems.

From disorders of the thyroid gland to nutritional deficiencies, metabolic disorders, and even conditions related to overweight and obesity, the ICD-10 Code E00-E89 range plays a pivotal role in ensuring accurate and efficient healthcare delivery.

Disclaimer: The information provided in this blog regarding the International Classification of Diseases (ICD) codes is intended for informational purposes only. We strive to offer accurate and up-to-date content. However, the ICD codes are subject to changes, updates, and modifications by authoritative bodies such as the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and other relevant healthcare organizations. These changes can occur due to advancements in medical knowledge, new diseases, evolving diagnostic criteria, or updates in medical terminology.

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